Applications

Add a new dimension to NIRS

Quantitative tissue oximetry without a-priori assumptions  and unprecedented reproducibility

PIONIRS devices

Other devices

Discover the applications

Clinical research

Our regional tissue oximeter is tailored to for the dynamic environments of Operating Rooms (OR) and Intensive Care Units (ICU). Designed to follow the patient through every phase of care – from pre-operative to post-operative – it ensures unwavering support for patients of all ages, from the most fragile population to adult subjects.

  • Cerebral and somatic oximetry
  • Endothelial health assessment
  • Long-term monitoring 
  • Intra-subject and longitudinal comparison
  • Acute respiratory distress syndrome bed-side monitoring
  • Suitable for rehabilitation procedures 

Selected publications

In the framework of the VASCOVID project, detection of the levels of impairment in microvascular oxygen consumption and reactive hyperemia in ICU patients.

JoVE Journal, Medicine

May, 2024

Read the article

NIRSBOX on quantitative fNIRS: motor cortex response to goal-oriented and not goal-oriented tasks.

Frontiers in Neuroscience
Vol. 17, July 2023

Read the article

Our NIRSBOX device in a study on motor cortex hemodynamics monitoring in freely walking healty subjects.

Neurophotonics
8(1), 015006, February 2021

Read the article

Sport science

The accurate assesssment of muscle oxygenation and oxygen consumption is pivotal in understanding athletic performance and physiological adaptations. Our advanced monitoring technology provides precise measurements of deoxygenated hemoglobin (HHbMb), oxygenated hemoglobin (HbMbO2), total hemoglobin (HbMbtot), and muscle oxygen saturation (SmO2), enabling comprehensive evaluation of local muscle oxygen consumption.

  • Accurate HHbMb, HbMbO2, HbMbtot and SmO2 assessment
  • Track performances over time 
  • Cardiopulmonary assessment, insight into muscle metabolism and oxygen consumption
  • Direct evaluation of differential pathlength factor (DPF) and correlation with adipose tissue thickness (ATT)
  • Reliable intra-subject measurements and longitudinal comparisons

Selected publications

Example of TD-NIRS applied to muscle fatigue assessment during isometric exercises.

Biomedical Optics Express
Vol. 11, Issue 12, December 2020

Read the article

In the framework of the VASCOVID project, assessment of very low (VLF) and low-frequency (LF) oscillations related to myogenic, neurogenic and endothelial activities.

Biomedical Optics Express

Vol. 14, Issue 11, October 2023

Read the article

Scientific research

No more complex TD-NIRS devices.  Our compact and plug-and-play TD-NIRS system, and the PIONIRS team will help pushing the boundaries of your research, achieving new levels of precision and accuracy. Easily integrate it with your existing setup. Whether your focus is on medical research, veterinary science, sports or any other field, our customizable solutions are designed to support and level-up your projects.

Contact us today to discuss how we can tailor our technology to meet your specific research needs.

  • Tissue characterization spectroscopy (ex-vivo and in-vivo organs) 
  • Identification of different chromophores (water content, cytochrome c-oxydase, …)
  • Aging and Muscular / Cerebral physiology
  • Clinical veterinary application
  • Food quality and agritech

Selected publications

Performance and reproducibility assessment across multiple NIRSBOX device replicas.

Proceedings Volume 11951,  2022

Read the proceeding

Multi-distance DCS device integrated with NIRSBOX device to monitor blood flow, tissue oxygenation, and oxygen metabolic rate.

Sensors

21(3), January 2021

Read the article

Non-invasive estimation of in vivo optical properties and hemodynamic parameters of domestic animals (horses, dogs, and sheep).

Frontiers Veterinary Science
Vol. 10, September 2023

Read the article