PIONIRS is proud to announce that Dr. Michele Lacerenza, CTO and co-founder of the company, will deliver an invited seminar at ShanghaiTech University on October 16, 2025.The talk, titled “Tissue Oximetry in Clinical Research: Quantitative Microvascular Biomarkers in Brain & Muscle”, will be hosted by Prof. Wuwei Ren from the School of Information Science and
Our team will participate as both sponsor and exhibitor at CARNet annual meeting 2025, which brings together international experts to discuss advances in cerebrovascular reactivity (CVR) assessment and neurovascular monitoring. Discover Our Latest Research: At PIONIRS, we have focused on using Time-Domain Near-Infrared Spectroscopy (TD-NIRS) to noninvasively measure cerebral oxygenation and microvascular reactivity. TD-NIRS provides
A new peer-reviewed paper in Nature Portfolio’s Scientific Reports shows that time-domain NIRS (TD-NIRS) with NIRSBOX can detect prefrontal cortex tissue oxygenation differences in children hospitalized with lower respiratory tract infections (LRTIs) compared with age- and sex-matched controls. In multivariate analysis, cerebral StO₂ emerged as an independent predictor of LRTI status, underscoring the added value
We’ve been busy building, validating, and iterating—and IEEE JSTQE thought it was worth a chat. In their latest issue, Michele Lacerenza and Mauro Buttafava discuss how PIONIRS brings rigorous TD-NIRS measurements out of the lab and into real-life research and care. The conversation reflects what drives us every day: quantitative accuracy, robust engineering, and tools
We’ll be attending the European College of Sport Science (ECSS) annual meeting as an exhibitor (𝐁𝐨𝐨𝐭𝐡 11)! Join us for HandsOn demos and live sessions featuring our NIRSBOX TD-NIRS oximeter — for quantitative and reliable muscle oximetry, trusted by elite research labs across Europe. Several cutting-edge scientific contributions at ECSS 2025 will feature the use
At PIONIRS, we’re always excited to see how our NIRSBOX-Q platform fuels innovation across biophotonics. In their recent Optica article, Eskandari and colleagues introduce a clever fusion of continuous-wave hyperspectral measurements with PIONIRS’s four-wavelength time-domain NIRS system—what they call “calibrated broadband NIRS,” or cbNIRS. From Concept to Quantitative Insight Traditional near-infrared spectroscopy can measures
We’ve achieved skin pigmentation bias-free tissue oximetry thanks to our TD-NIRS system NIRSBOX. A pivotal research study including the clinical + lab-grade measurement campaign confirms that TD-NIRS delivers bias-free measurements, regardless of skin pigmentation, paving the way for inclusive and precise clinical applications. 𝐊𝐞𝐲 𝐇𝐢𝐠𝐡𝐥𝐢𝐠𝐡𝐭𝐬 𝐟𝐫𝐨𝐦 𝐭𝐡𝐞 𝐕𝐚𝐥𝐢𝐝𝐚𝐭𝐢𝐨𝐧 𝐒𝐭𝐮𝐝𝐲: 🔸 350 subjects tested with Fitzpatrick
A new publication in neurophotonics sheds light on cerebral optical and hemodynamic properties in children. This study offers the first detailed reference values for pediatric brain physiology, covering quantitative measurements of hemoglobin concentrations, oxygenation, and optical properties. Why this study matters: 🔸It establishes a solid database (250 patients) for optical properties of cerebral tissue in children🔸
A deep dive into the characterization of TD-NIRS + DCS system with fast high-frequency acquisition rates and multiple interfiber distances for in-vivo measurements. Looking forward to seeing it used in clinical campaigns!
A pivotal new study sets the stage for improved cerebral and peripheral tissue oximetry monitoring in paediatrics. It is the first step towards establishing reference values for TD-NIRS tissue oximetry in children, a game-changer for precision medicine in pediatric care! 5 clinicians enrolled 350 children (ages 0-18) at Ospedale dei Bambini Buzzi in Milano, measuring
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