Category: Publications

PIONIRS clinical cartoon

Prefrontal brain oximetry in pediatric LRTIs: new Scientific Reports study using our NIRSBOX tissue oximeter.

Publicationspaper

A new peer-reviewed paper in Nature Portfolio’s Scientific Reports shows that time-domain NIRS (TD-NIRS) with NIRSBOX can detect prefrontal cortex tissue oxygenation differences in children hospitalized with lower respiratory tract infections (LRTIs) compared with age- and sex-matched controls. In multivariate analysis, cerebral StO₂ emerged as an independent predictor of LRTI status, underscoring the added value

PIONIRS featured in IEEE JSTQE: shaping the neurophotonics frontier

InterviewsPublications

We’ve been busy building, validating, and iterating—and IEEE JSTQE thought it was worth a chat. In their latest issue, Michele Lacerenza and Mauro Buttafava discuss how PIONIRS brings rigorous TD-NIRS measurements out of the lab and into real-life research and care. The conversation reflects what drives us every day: quantitative accuracy, robust engineering, and tools

Schema of experimental setup featuring NIRSBOX Q system.

Harnessing the Power of Hybrid NIRS: A Dive into Eskandari et al.’s cbNIRS Study

Publications

At PIONIRS, we’re always excited to see how our NIRSBOX-Q platform fuels innovation across biophotonics. In their recent Optica article, Eskandari and colleagues introduce a clever fusion of continuous-wave hyperspectral measurements with PIONIRS’s four-wavelength time-domain NIRS system—what they call “calibrated broadband NIRS,” or cbNIRS.   From Concept to Quantitative Insight Traditional near-infrared spectroscopy can measures

Advancing Pediatric Brain Research: a new Achievement!

Publications

A new publication in neurophotonics sheds light on cerebral optical and hemodynamic properties in children. This study offers the first detailed reference values for pediatric brain physiology, covering quantitative measurements of hemoglobin concentrations, oxygenation, and optical properties. Why this study matters: 🔸It establishes a solid database (250 patients) for optical properties of cerebral tissue in children🔸

New milestone in Pediatric Tissue Oximetry

Publications

A pivotal new study sets the stage for improved cerebral and peripheral tissue oximetry monitoring in paediatrics. It is the first step towards establishing reference values for TD-NIRS tissue oximetry in children, a game-changer for precision medicine in pediatric care! 5 clinicians enrolled 350 children (ages 0-18) at Ospedale dei Bambini Buzzi in Milano, measuring

A new study on brain activation during goal-oriented (and not) tasks.

Publications

Motor disorders are a global challenge, but guided neuro-motor rehabilitation can make a difference! Check out this latest study using the NIRSBOX device to measure motor cortex activity in-vivo and real-time during arm-raising actions. Link to publication: https://www.frontiersin.org/articles/10.3389/fnins.2023.1202705/full Motor cortex functional activation was studied for both goal-oriented & non-goal-oriented tasks in healthy subjects! We are setting the basis for understanding healthy motor cortex activation related

Motor cortex hemodynamic monitoring while walking? Take a look on SPIE Neurophotonics!

Publications

“For the first time to our knowledge, the hemodynamic motor cortex response was measured by TD fNIRS on the human brain during natural, freely walking exercises…” How many more boundaries will be broken thanks to compact TD-NIRS devices? Very interesting results have been published in this new study, made by the researchers of our team! Check it out at: https://doi.org/10.1117/1.NPh.8.1.015006 Abstract: Significance: This study is a preliminary step toward