A new paper in Experimental Physiology reports how prolonged bed rest alters skeletal muscle oxygen use in both young and older adults, using time-domain tissue oximetry with the PIONIRS NIRSBOX. In the study, the device was applied over the vastus medialis to track muscle oxygenation during transient ischaemia and to estimate resting muscle O₂ uptake
A new peer-reviewed paper in Nature Portfolio’s Scientific Reports shows that time-domain NIRS (TD-NIRS) with NIRSBOX can detect prefrontal cortex tissue oxygenation differences in children hospitalized with lower respiratory tract infections (LRTIs) compared with age- and sex-matched controls. In multivariate analysis, cerebral StO₂ emerged as an independent predictor of LRTI status, underscoring the added value
We’ve been busy building, validating, and iterating—and IEEE JSTQE thought it was worth a chat. In their latest issue, Michele Lacerenza and Mauro Buttafava discuss how PIONIRS brings rigorous TD-NIRS measurements out of the lab and into real-life research and care. The conversation reflects what drives us every day: quantitative accuracy, robust engineering, and tools
At PIONIRS, we’re always excited to see how our NIRSBOX-Q platform fuels innovation across biophotonics. In their recent Optica article, Eskandari and colleagues introduce a clever fusion of continuous-wave hyperspectral measurements with PIONIRS’s four-wavelength time-domain NIRS system—what they call “calibrated broadband NIRS,” or cbNIRS. From Concept to Quantitative Insight Traditional near-infrared spectroscopy can measures
A new publication in neurophotonics sheds light on cerebral optical and hemodynamic properties in children. This study offers the first detailed reference values for pediatric brain physiology, covering quantitative measurements of hemoglobin concentrations, oxygenation, and optical properties. Why this study matters: 🔸It establishes a solid database (250 patients) for optical properties of cerebral tissue in children🔸
A deep dive into the characterization of TD-NIRS + DCS system with fast high-frequency acquisition rates and multiple interfiber distances for in-vivo measurements. Looking forward to seeing it used in clinical campaigns!
A pivotal new study sets the stage for improved cerebral and peripheral tissue oximetry monitoring in paediatrics. It is the first step towards establishing reference values for TD-NIRS tissue oximetry in children, a game-changer for precision medicine in pediatric care! 5 clinicians enrolled 350 children (ages 0-18) at Ospedale dei Bambini Buzzi in Milano, measuring
Motor disorders are a global challenge, but guided neuro-motor rehabilitation can make a difference! Check out this latest study using the NIRSBOX device to measure motor cortex activity in-vivo and real-time during arm-raising actions. Link to publication: https://www.frontiersin.org/articles/10.3389/fnins.2023.1202705/full Motor cortex functional activation was studied for both goal-oriented & non-goal-oriented tasks in healthy subjects! We are setting the basis for understanding healthy motor cortex activation related
Great news about reproducibility in fabrication of tissue-mimicking solid phantoms! A new paper by Phisics Department of Politecnico di Milano and CNR IFN, exploiting our NIRSBOX device. Another step towards standardization in diffuse optics. Take a look on Journal of Biomedical Optics, at: https://doi.org/10.1117/1.JBO.27.7.074713
On 18th – 22nd October 2021, the Society of fNIRS will host the fNIRS 2021 Virtual Conference. PIONIRS is proud to be a Platinum Sponsor of such an exciting and important event for the NIRS community! Also, don’t miss the talk of our CTO Michele, about performance characterization of our NIRSbox device: October 19, 2021
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